{"id":1820,"date":"2025-08-20T23:34:12","date_gmt":"2025-08-20T23:34:12","guid":{"rendered":"https:\/\/farbio.edu.bo\/iifb\/?page_id=1820"},"modified":"2025-08-21T08:13:59","modified_gmt":"2025-08-21T08:13:59","slug":"bioquimica-molecular","status":"publish","type":"page","link":"https:\/\/farbio.edu.bo\/iifb\/?page_id=1820","title":{"rendered":"Bioqu\u00edmica Molecular"},"content":{"rendered":"\t\t
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\u00c1rea
Bioqu\u00edmica Molecular<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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El \u00c1rea de Bioqu\u00edmica Molecular se dedica a desarrollar soluciones innovadoras para enfrentar problemas emergentes y reemergentes en el marco del enfoque de \u201c<\/span>Una Sola Salud<\/span><\/a>\u201d, esto en estrecha colaboraci\u00f3n con instituciones cient\u00edficas a nivel local, nacional y regional. Para ello, se emplean t\u00e9cnicas avanzadas de an\u00e1lisis y procesamiento de ADN y ARN con el objetivo de obtener productos y bioinsumos de alto valor.<\/span><\/p>

Esta \u00e1rea cuenta con capacidades instaladas para realizar an\u00e1lisis bioinform\u00e1ticos que incluyen el control de calidad de secuencias, identificaci\u00f3n de organismos, ensamblaje de genomas y metagenomas, as\u00ed como su anotaci\u00f3n funcional y estructural. Adem\u00e1s, integra herramientas de biotecnolog\u00eda microbiana, ingenier\u00eda gen\u00e9tica, s\u00edntesis biol\u00f3gica, preservaci\u00f3n y documentaci\u00f3n de la diversidad microbiana (bancos de cepas), identificaci\u00f3n molecular, bioinform\u00e1tica, nanobiotecnolog\u00eda y bioprocesos, lo que le confiere una gran flexibilidad y adaptabilidad<\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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El \u00c1rea est\u00e1 conformada por los siguientes laboratorios:<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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Taxonom\u00eda y diagn\u00f3stico molecular<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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\"\"<\/figure>

En esta unidad se desarrollan de kits de diagn\u00f3stico molecular y tambi\u00e9n se detecta presencia microorganismos (par\u00e1sitos, bacterias, hongos, virus) de distintas especies por PCR convencional, PCR en tiempo real, secuenciaci\u00f3n de nueva generaci\u00f3n (tecnolog\u00eda Ilumina y Nanopore), an\u00e1lisis de restricci\u00f3n y an\u00e1lisis por DGGE (Denaturing gradient gel electrophoresis). Asimismo, se cuenta con una amplia colecci\u00f3n de metagenomas y genomas de microoraganismos. Finalmente, tambi\u00e9n se realizan estudios de epidemiolog\u00eda basada en aguas residuales: din\u00e1mica de la resistencia antimicrobiana (genes de resistencia antimicrobiana y bacterias resistentes a antibi\u00f3ticos).<\/p><\/div><\/div>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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Tecnolog\u00eda del DNA recombinante y bioinform\u00e1tica<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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\"\"<\/figure>

En esta unidad se aplican t\u00e9cnicas de ingenier\u00eda gen\u00e9tica y biolog\u00eda sint\u00e9tica<\/p><\/div><\/div>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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Unidad de biocontrol <\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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\"\"<\/figure>

En esta unidad se mantienen bancos de bacteri\u00f3fagos, probi\u00f3ticos y microorganismos en general. Se realiza desarrollo de bioinsumos y biof\u00e1rmacos, gen\u00f3mica y prote\u00f3mica, ingenierias de proteinas y gen\u00e9tica, y s\u00edntesis biol\u00f3gica.<\/p><\/div><\/div>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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Resumen de las capacidades instaladas<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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  • Diagn\u00f3stico molecular<\/span><\/li>
  • Identificaci\u00f3n taxon\u00f3mica molecular de microorganismos (par\u00e1sitos, bacterias, hongos y virus)\u00a0<\/span><\/li>
  • Vigilancia molecular – epidemiolog\u00eda basada en aguas residuales<\/span><\/li>
  • Desarrollo de bioinsumos y biofarmacos<\/span><\/li>
  • Gen\u00f3mica<\/span> y prote\u00f3mica<\/span><\/li>
  • Ingenieria de proteinas<\/span><\/li>
  • Ingenier\u00eda gen\u00e9tica<\/span><\/li>
  • Biologia sintetica<\/span><\/li>
  • Bioinformatica<\/span><\/li>
  • Colecci\u00f3n de metagenomas y genomas de microoraganismos<\/span><\/li>
  • Banco de bacteri\u00f3fagos\u00a0<\/span><\/li>
  • Banco de probi\u00f3ticos <\/span><\/li><\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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    \u00c1rea Bioqu\u00edmica Molecular<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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    \nEquipo de trabajo\n<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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    Mar\u00eda Teresa Alvarez Aliaga Ph.D.<\/div>\n\t\t\t\n\t\t\t\t\t\t
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    (Investigadora titular)<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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    Lic. Marcelo Gutierrez Valverde<\/div>\n\t\t\t\n\t\t\t\t\t\t
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    (Doctorando-Uppsala University)<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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    Daniel Salas Veizaga Ph.D.<\/div>\n\t\t\t\n\t\t\t\t\t\t
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    (Investigador titular) <\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"

    \u00c1rea Bioqu\u00edmica Molecular El \u00c1rea de Bioqu\u00edmica Molecular se dedica a desarrollar soluciones innovadoras para enfrentar problemas emergentes y reemergentes […]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"site-sidebar-layout":"no-sidebar","site-content-layout":"","ast-site-content-layout":"full-width-container","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"disabled","ast-breadcrumbs-content":"","ast-featured-img":"disabled","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"class_list":["post-1820","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/farbio.edu.bo\/iifb\/index.php?rest_route=\/wp\/v2\/pages\/1820","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/farbio.edu.bo\/iifb\/index.php?rest_route=\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/farbio.edu.bo\/iifb\/index.php?rest_route=\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/farbio.edu.bo\/iifb\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/farbio.edu.bo\/iifb\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=1820"}],"version-history":[{"count":26,"href":"https:\/\/farbio.edu.bo\/iifb\/index.php?rest_route=\/wp\/v2\/pages\/1820\/revisions"}],"predecessor-version":[{"id":2048,"href":"https:\/\/farbio.edu.bo\/iifb\/index.php?rest_route=\/wp\/v2\/pages\/1820\/revisions\/2048"}],"wp:attachment":[{"href":"https:\/\/farbio.edu.bo\/iifb\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=1820"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}